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PalC/Resources/Learning Materials/Doctors/[Journal article] Clinical Frailty Scale versus Geriatric-8 in predicting quality of life among older adults receiving curative cancer treatment
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Year 2025
June 2025

[Journal article] Clinical Frailty Scale versus Geriatric-8 in predicting quality of life among older adults receiving curative cancer treatment

17 Jun 2025

Authors: Wen Yang Goh, Hui Min Tan, Hui Lin Teo, Elise K. Y. Vong, Francis C. H. Ho, Ming Yann Lim & Allyn Y. M. Hum 

Published in: Supportive Care in Cancer. Published online: 06 June 2025. DOI: https://doi.org/10.1007/s00520-025-09616-1

Summary points:

  1. Clinical Frailty Scale (CFS) effectively identifies quality-of-life concerns in older adults with cancer undergoing curative treatment, particularly in physical and psychoemotional domains.
  2. Frail older adults (CFS ≥4) experience significantly diminished quality of life at diagnosis and during treatment, with improvement observed by three months post-treatment initiation.
  3. Targeted supportive care interventions during cancer treatment are essential to maintain quality of life in older adults whilst pursuing life-prolonging therapy.

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