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Year 2023
November 2023

[Journal article] Prognostic Factors of Mortality in Non-Chronic Obstructive Pulmonary Disease Chronic Lung Disease: A Scoping Review

08 Nov 2023

Authors: Sheryl Hui Xian Ng, Gin Tsen Chai, Pradeep Paul George, Palvinder Kaur, Wan Fen Yip, Zi Yan Chiam, Han Yee Neo, Woan Shin Tan, Allyn Hum

Published in: Journal of Palliative Medicine. Published online: 13 Sep 2023. http://doi.org/10.1089/jpm.2023.0263 

Summary points:

  1. In addition to chronic obstructive lung disease, we identified interstitial lung disease, connective tissue disease-related interstitial lung disease and bronchiectasis as chronic lung conditions where prognostic factors for 1-3 year mortality have been studied.
  2. Prognostic factors in these non-COPD chronic lung diseases spanned ten domains, with older age, lower forced vital capacity and lower carbon monoxide diffusing capacity being the most frequently examined prognostic factors.
  3. Most of these studies were at a moderate-to-high risk of bias due to limitations in statistical methodology applied, and findings from these studies should be used to prioritise candidate risk factors for further study.

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