(65) 6500 7269

  • Subscribe to Mailing List

    To receive the latest news and updates on PalC courses.

  • By submitting this form, you hereby agree that PalC may collect, store, process, and disclose your personal data that you provide in this form for training administration, and for the purpose of sending you updates about the various events, courses, seminars, and related activities organised or co-organised by PalC, in accordance with the Personal Data Protection Act.

  • This field is for validation purposes and should be left unchanged.
Photo by LKCMedicine
Year 2021
May 2021

[Journal article] The Impact of a Standardised Ketamine Step Protocol for Cancer Neuropathic Pain

25 May 2021

Authors: Mahrley T. Provido-Aljibe, Choon Meng Yee, Zhi Jun Carin Low, Allyn Hum

Published in: Progress in Palliative Care 2021; doi: 10.1080/09699260.2021.1922146

Summary points:

  • Patient selection is very important. A positive response to ketamine is based on careful identification of patients with predominantly neuropathic mechanism of pain.
  • Our study used ketamine for patients demonstrating central sensitisation reflected on the ECS-CP. Ketamine as a NMDA- receptor agent winds down opioid effect decreasing opioid tolerance at a lower dose, an effect of ketamine on patients with neuropathic pain syndromes. 
  • The well-defined STEP PROTOCOL is safe and effective method to standardised the titration of ketamine and duration of its use. The use of psychotropic medications increases the tolerability of ketamine with none to low severity of side effects.

Our Partners